The 2 big differences between the sand and gravel are this:
1. Intake tubes for HOB and Cannister filters. Get them UP AND AWAY from the bottom of the tank. Sand and impellers don't mix.
2. Water changes. Gotta watch how close you get the siphon. I have very fine sand so it will get sucked up real easy. Heavier sand will stay put a little better, but you can still suck a bunch out if ya aint paying attention.
The one other thing ya gotta do is "swoosh" the sand around once a week or so. The sand is actually "heavy" and gets packed pretty dense so it allows buildup of bad gases. These if left undisturbed over long periods, when released can be really harmful to the fish. So by "swooshing" every now and then, you remove that buildup. Prior to "swooshing".....remember rule #1 !!! So just swoosh it enough to disturb it. Don't get nuts!